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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBCEL
All Species:
27.27
Human Site:
S250
Identified Species:
50
UniProt:
Q5QJ74
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5QJ74
NP_001123519.1
424
48195
S250
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001107143
424
48146
S250
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Dog
Lupus familis
XP_546476
474
54071
S300
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5W3
424
48013
S250
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Rat
Rattus norvegicus
Q5PQJ7
424
48027
S250
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505426
448
50738
S274
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Chicken
Gallus gallus
XP_427094
424
48312
S250
E
D
I
D
K
L
N
S
F
P
K
L
E
E
V
Frog
Xenopus laevis
Q5U508
522
58770
K325
C
V
I
N
E
L
H
K
L
L
H
L
E
S
L
Zebra Danio
Brachydanio rerio
Q5U378
521
59024
K323
R
V
V
N
E
L
E
K
L
P
S
L
V
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610562
459
53124
K282
A
A
I
D
E
L
A
K
F
S
E
L
R
N
L
Honey Bee
Apis mellifera
XP_625182
456
52092
R260
D
D
V
E
R
L
A
R
F
P
A
L
K
S
L
Nematode Worm
Caenorhab. elegans
Q9BLB6
253
28846
I83
I
N
Y
I
A
P
D
I
A
T
K
L
P
N
L
Sea Urchin
Strong. purpuratus
XP_795187
436
49499
L263
K
L
N
E
F
P
S
L
K
E
A
L
V
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
89
N.A.
97.4
96.9
N.A.
89
89.3
24.3
23.2
N.A.
38.5
37.9
20.7
36.4
Protein Similarity:
100
N.A.
99.7
89
N.A.
99.5
99.5
N.A.
92.1
94
42.5
40.6
N.A.
55.7
58.3
35.3
58.2
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
26.6
20
N.A.
33.3
33.3
13.3
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
100
100
53.3
46.6
N.A.
53.3
73.3
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
0
16
0
8
0
16
0
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
62
0
62
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
0
16
24
0
8
0
0
8
8
0
62
54
0
% E
% Phe:
0
0
0
0
8
0
0
0
70
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
70
8
0
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
54
0
0
24
8
0
62
0
8
8
0
% K
% Leu:
0
8
0
0
0
85
0
8
16
8
0
100
0
0
39
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
16
0
0
54
0
0
0
0
0
0
16
0
% N
% Pro:
0
0
0
0
0
16
0
0
0
70
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
0
0
8
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
8
54
0
8
8
0
0
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
16
16
0
0
0
0
0
0
0
0
0
16
0
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _